Prof Alejandro (Alex) Frangi obtained a BSc/MSc in Telecommunications Engineering from the Technical University of Catalonia (Barcelona) in 1996. He pursued his PhD in Medicine at the Image Sciences Institute of the University Medical Centre Utrecht University on model-based cardiovascular image analysis. He is the Diamond Jubilee Chair in Computational Medicine at the University of Leeds, UK, with joint appointments at the School of Computing and the School of Medicine. He leads the Centre for Computational Imaging and Simulation Technologies in Biomedicine. He is also a Royal Academy of Engineering Chair in Emerging Technologies, Visiting Professor at KU Leuven, Belgium. Prof Frangi has main research interests at the crossroad of medical image analysis and modelling, emphasising machine learning (phenomenological models) and computational physiology (mechanistic models).